Immunoglobulin Fc Fragments

Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.

Also Known As:

Immunoglobulin Fc Fragment; Immunoglobulins, Fc; Immunoglobulins, Fc Fragment; Fc Fragment Immunoglobulins; Fc Fragment, Immunoglobulin; Fc Fragments, Ig; Fc Fragments, Immunoglobulin; Fragment Immunoglobulins, Fc; Fragment, Fc; Fragments, Ig Fc; Immunoglobulin, Fc; Fc Fragment; Fc Fragments; Fc Immunoglobulin; Fc Immunoglobulins; Ig Fc Fragments

Pharmalogical Action Categories:

Immunologic Factors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Blood Proteins: 12679
    - Serum Globulins: 555
      - Immunoglobulins: 30911
        Immunoglobulin Fragments: 979
        Immunoglobulin Fc Fragments: 300
        Immunoglobulin Constant Regions: 8
        Immunoglobulin Fc Fragments: 300
    - Immunoproteins: 43
      - Immunoglobulins: 30911
        Immunoglobulin Fragments: 979
        Immunoglobulin Fc Fragments: 300
        Immunoglobulin Constant Regions: 8
        Immunoglobulin Fc Fragments: 300
  - Globulins: 3119
    - Serum Globulins: 555
      - Immunoglobulins: 30911
        Immunoglobulin Fragments: 979
        Immunoglobulin Fc Fragments: 300
        Immunoglobulin Constant Regions: 8
        Immunoglobulin Fc Fragments: 300
- Peptides: 84029
  - Peptide Fragments: 379
    - Immunoglobulin Fragments: 979
      - Immunoglobulin Fc Fragments: 300

Antonella Ciarelli Selected Research

Antonella Ciarelli Research Topics

Disease

Drug/Important Bio-Agent (IBA)